A 19Y/M with fever thrombocytopenia

 

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 A 19year old male came to the opd with complains of fever since 1 year.C/O SOB since 15 to 20 days



HOPI:

 

Patient was apparently asymptomatic 1 year ago then he developed lowgrade intermittent  type of fever which aggravated since 15 days, mainly during the night time,temporarily relieved on medication.It was associated with bodypains and headache, low backache.Not associated with cold and cough, burning micturition and rash on  body.He complains of SOB  since 15 days which is present even on rest,which aggravates after having food.Bloating and chesttightness are present.

Patient complains of bleeding gums since 2 days

Cold is present since 3months after drinking softdrinks/colditems.





PAST HISTORY

N/K/C/O DM, TB, epilepsy, CVA, CAD, thyroid disorders and bronchial asthma.


FAMILY HISTORY:

Not significant


PERSONAL HISTORY: 


Diet :Mixed

Apetite:Normal

Bowel and bladder Movements:Regular

Sleep:Adequate

No  allergies and addictions.



Daily routine: Patient wakes up at 7AM and has some breakfast at 8:30AM  and goes to college at 9AM.He skips his lunch.He comes back from college at 5 PM and eats some food at 6:30PM.He goes to play till 8pm.He skips dinner.He studies till 10pm for 2 hours.He sleeps by 11am.

He goes to college regularly despite his fever but 15 days back he could not eat properly due to   SOB while eating.

His dailyroutine is not changed due to his symptoms.


Course in the hospital:


Patient came with above complaints and necessart nivestigations and thorough clinical examination was done.

Hemogram was done on 2/8

Hb :13.8mg/dl

plateletcount:78000lakhs/cumm

Widal test,rapid dengue test,blood for MP strip test was done .They are negative.Blood,urine and sputum was sent for culture and sensitivity.It showed no growth.

Sputum was sent for CBNAAT.MTB was not detected.

On monitoring temperature ,feverspikes were not seen .It was lowgrade fever.Patient was complaining of backpain.Dorsal spine xray was done.It was normal.Patient was complaining of bleeding gums since 2 days.His platelets trends were fluctuating.

Peripheral smear was done .It showde giant platelets.

Hemogram was repeated on 6/8/23

Hb:14

Plt count:68000lakhs/cumm


6 minute walk test was done:


Before 6min walk test

Spo2-99 %

RR-20 cpm

PR-75 bpm

BP-100/70 mmHg


After 6min walk test

Spo2- 98 %

RR-22cpm

PR-78bpm

BP-100/80 mmHg.

Patient was diagnosed with immunethrombocytopenia and symptomatic treatment was started.



Platelet trends :














GENERAL EXAMINATION:

On examination patient is conscious, coherent, cooperative 

No pallor, icterus, cyanosis, clubbing, lymphadenopathy, edema 

VITALS:

Temp-Afebrile

PR-64bpm 

RR: 22Cpm 

BP:110/70mm Hg 

Spo2:99% at room air 

GRBS charting: 98mg/dL


Systemic examination:

Per abdomen:

Soft,Nontender

RS:

bilateral air entry is present.

Normal vesicular breath sounds are heard.

CVS:

S1S2 heard.No murmurs

CNS: 

HMF+,NFND


Provisional Diagnosis:

IMMUNE THROMBOCYTOPENIA


Investigations:

Hemogram:(2/8/23)




6/8/23




CUE:






LFT:


Peripheral smear:







Reticulocyte count


RFT:


ECG:


Chestxray:



Dorsal spine XRay:












Serology:negative

BGT:B+ve

RBS:79mg/dl

Widal test: negative

Rapid dengue:negative

Blood for MP strip test:negative

CBNAAT:MTB not detected

Blood/urine/sputum culture: No growth is detected

PT:17sec

APTT:35sec

INR:1.2

PLBS:114mg/dl

FBS:80mg/dl

HBa1c:6.4mg/dl

CRP:negative






Clinical images:













Treatment:

1)Tab Dolo 650 mg/PO/TID

2)Monitor vitals 4 th hourly









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